Endocrine Abstracts

Aim: To evaluate sleep architecture of patients with Cushing’s disease (CD) and to explore whether agouti-related peptide (AgRP) leptin, and interleukin-6 (IL-6) play a permissive role in sleep alterations.Methods: We performed polysomnography on 26 patients with active CD and age 26 age- and sex-matched control subjects. Blood samples were obtained from all participants for the analyses of AgRP, leptin, and IL-6. The laboratory and sleep-related pa...

Aim: To investigate the volumetric changes in cortical and subcortical deep gray matter (GM) structures and cognitive alterations in patients with mild autonomous cortisol secretion (MACS). We also sought to assess whether the anticipated changes in brain volume and cognitive functions of the patients with MACS differ from the changes in patients with overt Cushing’s Syndrome (CS). Methods: In this cross-sectional study, volumes of the cortex, hippo...

Aim: To determine the prevalence of impulse control disorder (ICD) in patients with Cushing’s disease (CD) treated with cabergoline (CBG) compared to CBG-naive patients with CD.Methods: We performed a cross-sectional study in patients with CD followed at 5 referral centers based in Istanbul. Eligible patients with CD were those with current CBG treatment for ≥ 3 months. Eligible controls were CBG-naive patients with CD that were matched for ag...

Background/Aim: In literature, many previous studies adressed that Gender-affirmig Hormone Therapy (GAHT) improves the factors affecting social functioning such as self-esteem, mental well-being, behavioral health and quality of life. In this study, we aimed to quantitatively evaluate the effects of the GAHT on social functioning using a psychiatric scale in people with female-to-male (FtM) in Türkiye.Methods: The single center, cross-sectional stud...

Transphobia is expressed as negative attitudes, emotions and actions towards transgender individuals or transsexualism. The aim of this study is to investigate the existence of transphobic approaches towards transgender individuals in physicians in different clinics that play an active role in the gender transition process. It was planned to include physicians from the disciplines of psychiatry, endocrinology, gynecology, urology and plastic surgery. A questionnaire was sent t...